Christoph Lohmann
Prof. Dr. med. Christoph Lohmann
Jessica Bertrand
Leiterin Experimentelle Orthopädie
Prof. Dr. rer. nat. Jessica Bertrand


Einen Einblick in die Veröffentlichungen aus unserem Haus finden Sie im Forschungsportal Sachsen-Anhalt.

Publikationen 2016:

Gronau T, Krüger K, Prein C, Aszodi A, Gronau I, Iozzo RV, Mooren FC, Clausen-Schaumann H, Bertrand J, Pap T, Bruckner P, Dreier R. Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin. Ann Rheum Dis. 2016 Jul 4. pii: annrheumdis-2016-209319.

Drynda A, Ren Q, Buchhorn GH, Lohmann CH. The induction of CXCR4 expression in human osteoblast-like cells (MG63) by CoCr particles is regulated by the PLC-DAG-PKC pathway. J Biomed Mater Res B Appl Biomater. 2016 Aug 9.

Singh G, Deutloff N, Maertens N, Meyer H, Awiszus F, Feuerstein B, Roessner A, Lohmann CH. Articulating polymethylmethacrylate (PMMA) spacers may have an immunomodulating effect on synovial tissue. Bone Joint J. 2016 Aug;98-B(8):1062-8.

Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Pap T, Püschel K, Rüther W, Niemeier A. Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder. Osteoarthritis Cartilage. 2016 Jul 5. pii: S1063-4584(16)30171-6.

Hawellek T, Hubert J, Hischke S, Vettorazzi E, Wegscheider K, Bertrand J, Pap T, Krause M, Püschel K, Rüther W, Niemeier A. Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population. J Orthop Res. 2016 Mar 11

Berth A, März V, Wissel H, Awiszus F, Amthauer H, Lohmann CH. SPECT/CT demonstrates the osseointegrative response of a stemless shoulder prosthesis. J Shoulder Elbow Surg. 2016 Apr;25(4):e96-103. doi:

Stärke C, Winkelmann U, Glüge S, Becker R, Lohmann CH, Winkelmann U. Interference screw fixation of free tendon grafts: significant time-dependent decrease of the initial contact forces. Knee Surg Sports Traumatol Arthrosc. 2016 Jul;24(7):2353-8.


Publikationen 2015:

Chamaon K, Barber H, Awiszus F, Feuerstein B, Lohmann CH. Expression of CD11c in periprosthetic tissues from failed total hip arthroplasties. J Biomed Mater Res A. 2016 Jan;104(1):136-44. doi: 10.1002/jbm.a.35549. Epub 2015 Aug 20.

Dankbar B, Fennen M, Brunert D, Hayer S, Frank S, Wehmeyer C, Beckmann D, Paruzel P, Bertrand J, Redlich K, Koers-Wunrau C, Stratis A, Korb-Pap A, Pap T. Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice. Nat Med. 2015 Aug 3. doi: 10.1038/nm.3917.

Polte T, Petzold S, Bertrand J, Schütze N, Hinz D, Simon JC, Lehmann I, Echtermeyer F, Pap T, Averbeck M. Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation. Nat Commun. 2015 Jul 13;6:7554.

Singh G, Nuechtern JV, Meyer H, Fiedler GM, Awiszus F, Junk-Jantsch S, Bruegel M, Pflueger G, Lohmann CH. Particle characterisation and cytokine expression in failed small-diameter metal-on-metal total hip arthroplasties. Bone Joint J. 2015 Jul;97-B(7):917-23

Dobrindt O, Amthauer H, Krueger A, Ruf J, Wissel H, Grosser OS, Seidensticker M, Lohmann CH. Hybrid SPECT/CT for the assessment of a painful hip after uncemented total hip arthroplasty. BMC Med Imaging. 2015 Jun 2;15:18

Bergschmidt P, Bader R, Ganzer D, Hauzeur C, Lohmann CH, Krüger A, Rüther W, Tigani D, Rani N, Esteve JL, Prats FL, Zorzi C, Madonna V, Rigotti S, Benazzo F, Rossi SM, Mittelmeier W. Prospective multi-centre study on a composite ceramic femoral component in total knee arthroplasty: Five-year clinical and radiological outcomes. Knee. 2015 Jun;22(3):186-91


Publikationen 2014:

Sherwood J, Bertrand J, Nalesso G, Poulet B, Pitsillides A, Brandolini L, Karystinou A, De Bari C, Luyten FP, Pitzalis C, Pap T, Dell'Accio F. A homeostatic function of CXCR2 signalling in articular cartilage. Ann Rheum Dis. 2014 Aug 18.

Wixler V, Cromme C, Retser E, Meyer LH, Smyth N, Mühlenberg K, Korb-Pap A, Koers-Wunrau C, Sotsios Y, Bassel-Duby R, Baeten D, Tak PP, Niederreiter B, Redlich K, Bertrand J, Skryabin BV, Ludwig S, Pap T. FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis. Ann Rheum Dis. 2014 Aug 14.

Höfling S, Scharnert J, Cromme C, Bertrand J, Pap T, Schmidt MA, Rüter C. Manipulation of pro-inflammatory cytokine production by the bacterial cell-penetrating effector protein YopM is independent of its interaction with host cell kinases RSK1 and PRK2. Virulence. 2014 May 5;5(6). [Epub ahead of print]


Publikationen 2013:

Lindemann O., Umlauf D., Frank S., Schimmmelpfennig S., Bertrand J., Pap T., Hanley PJ, Fabian A., Dietrich A. and Schwab A. TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils J Immunol. 2013; 190(11):5496-505

Frank S., Peters M.A., Wehmeyer C., Strietholt S., Koers-Wunrau C., Bertrand J., Heitzmann M., Hillmann A., Sherwood J., Seyfert C., Gay S., Pap T.  Regulation of matrix metalloproteinase-3 and -13 by SUMO-2/3 through the transcription factor NF-κB. Ann Rheum Dis 2013 ;72(11): 1874-81.


Publikationen 2012:

Schmidt-Lauber C., Pap T., Fischer M., Victor M., Heitzmann M., Hansen U., Fobker M., Pavenstädt H., Sindic A., Edemir B., Harrach S., Köllmann K., Schlatter E., Bertrand J. and Ciarimboli G. Importance of transporters and their pathology-induced regulation for drug delivery into RA synovial fibroblasts at the example of the triad Imatinib. PLos ONE, 2012;7(12):e52247

Bertrand J.*, Stange R.*, Echtermeyer F., Hidding H., Godmann L., Nalesso G., Pap T., Bruckner P., Dell'Accio F., Dreier R. Regulation of embryonic bone development and fracture repair by Syndecan-4. Arthritis Rheum., 2012; 65(3):743-52.* both authors contributed equally

Fabian A, Bertrand J, Lindemann O, Pap T, Schwab A. Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration. Pflugers Arch. 2012;464(6):623-30.

Bertrand J.*, Nitschke Y.*, Fuerst M., Ruether W., Hermann S., Schäfers M., Nalesso G., Sherwood J., Rutsch F., Dell’Accio F. and Pap T. Decreased levels of Nucleotide Pyrophosphatase Phosphodiesterase NPP1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Ann Rheum Dis 2012;71:1249–1253. * both authors contributed equally


Publikationen 2011:

Nalesso G., Sherwood J., Bertrand J., Pap T., Ramachandran M., De Bari C., Pitzalis C.,dell’Accio F. WNT-3A modulates articular chondrocyte phenotype by activating both canonical and non canonical pathways. J Cell Biol. 2011;193(3):551-64.


Publikationen 2009:

Echtermeyer F. *, Bertrand J.*, Dreier R., Neugebauer K., Lee YJ, Song YW, Fürst M., Herzog C. and Pap T. Syndecan-4 regulates enchondral ossification and cartilage degradation in osteoarthritis. Nat Med. 2009;15(9):1072-6. * both authors contributed equally

Fuerst M.*, Bertrand J.*, Lammers L., Dreier R., Echtermeyer F., Nitschke Y., Rutsch F., Schäfer F., Niggemeyer O., Steinhagen J., Dreimann M., Pap T. and Rüther W. Prevalence and structure of calcium crystals in advanced osteoarthritis of the knee. Arthritis Rheum. 2009;60(9):2694-703. * both authors contributed equally


Letzte Änderung: 04.01.2019 - Ansprechpartner:

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